[Takayasu's disease. A review of the literature. A study of a familial case of Takayasu's arteritis and the possible associations with type-1 diabetes mellitus]. / La malattia di Takayasu. Rassegna della letteratura. Studio di un caso familiare di arterite di Takayasu e possible associazione con il diabete mellito di tipo 1.

After a brief review of the literature on Takayasu's disease with particular emphasis on its relationship with the HLA system, the case of a mother and daughter both suffering from Takayasu's type systemic arteritis is presented with particular reference to a possible association with type-I diabetes mellitus (IDDM) in the light of the patient's HLA typing results.

[Measuring venous pressure with the Doppler technic: standardization of the method]. / Mesure de la pression veineuse avec le Doppler: standardisation de la méthode.

Using the Doppler, we have studied the venous pressure, with the patients standing, of 6,172 legs. In a normal subject, the index of average pressure is 59 mmHg in the posterior tibial vein, and 58 mmHg in the long saphenous vein. Where there are varicose veins, the average pressure is 90 and 96 mmHg in the deep veins and in the superficial veins. In the case of post-phlebitic syndrome, the average index is 101 and 102 mmHg in the deep and superficial veins. In this work, the credibility of the method is discussed, and in particular, in comparison with the surgical methods, and its usefulness in current phlebological practice is defined.

[On some experimental conditions possibly influencing the correct measurement of venous pressure by Doppler method]. / Su alcune condizioni sperimentali che possono influenzare il corretto rilievo delle pressioni venose Doppler.

Measurement of venous pressure by means of the Doppler method applied to the posterior tibial vein and to the internal and external saphenous veins is subject to error which depends on the observer's technique. We have therefore sought to ascertain whether and how differences in measurement techniques could affect the results of venous pressure determination in 50 subjects. We have observed that: --Measured pressure are higher when the duration of the test is prolonged, probably because the cuff remains inflated too long. --Of several consecutive determinations, the first and second yield generally higher values, that decrease and remain stable thereafter through the 5th measurement, following the initial loss of venous tone. --Venous pressure is lower as the measurement site is moved more proximally, as predicted by the expected pressure gradient along the venous circulation; the decrease could also be affected by local changes of vein compliance.

[Plethysmographic researches on the beginning and duration of the pharmacological action of an isosorbide dinitrate drugs with prolonged action (author's transl)]. / Indagini pletismografiche sull'inizio e sulla durata dell'azione farmacodinamica di un preparato di isosorbide dinitrato ad azione protratta.

Taking into consideration a previous work, where we experimented the pharmacological action of different products of nitrite retard and from which resulted the absolute superiority of isosorbide dinitrate, we considered interesting to repeat the experimentation with a new form of isosorbide dinitrate characterized by an action duration more prolonged in the time owing to the particular freeing of the active principle. In 20 patients free from peripheral vasculopathy it was enregistered the rheogram with derivation back-feet-big toe in base condition and at 1st, 3rd, 5th and 10th hour from the administration of Nitrosorbide Retard 20 mg. The product action, put in evidence by the appearance of the typical pulse by nitrite, begins the first hour, it reaches the maximum at the 5th hour on average and it clearly lasts until the 10th hour. Therefore it is demonstrated the practical usefulness of this product in the daily clinical medicine considered its characteristics of action rapidity, duration and steadfastness.

[Hypertension in young man. Epidemiologic investigation in students of an Italian secondary school (author's transl)]. / Ipertensione arteriosa giovanile. Indagine epidemiologica in un liceo di Roma.

The investigation carried out on a group of 1221 students (aged 13-19) of an Italian secondary school shows (19.6%) prevalence of high blood pressure. The prevalence was calculated assuming as hypertensive people with blood pressure higher than an arbitrary limit of 140/90 mmHg. The means, standard deviations and 95th percentiles for systolic and diastolic pressure for each age and sex were also calculated. In a follow up of 6 months the percentage of students with BP > 140/90 mmHg decreased from 6.5% to 3.5%. Statistical analysis of 19 items of a questionnaire distributed to be filled to the students shows interesting correlations between BP values, hypertension in relatives and obesity.